soluble intracellular adhesion molecule-1 in the serum of colon and gastric cancer patients

Soluble Intracellular Adhesion Molecule-1 in the Serum of Colon and Gastric Cancer Patients

Clinical significance of serum soluble intercellular adhesion molecule 1 in gastric cancer.

We studied the correlation between serum soluble intercellular molecule 1 (sICAM-1) and clinicopathological features in patients with gastric cancer. The impact of sICAM-1 on prognosis was also evaluated. The sera from 224 patients with gastric cancer, 44 healthy individuals, and 35 patients with benign gastrointestinal diseases (4 patients with submucosal stomach tumors, 6 patients with gastri...

Serum Level of Soluble Vascular Adhesion Molecule 1 in Patients with Rectal Cancer

Aim: Vascular adhesion molecule 1 (VCAM-1) plays an important role in solid tumor enlargement and/or metastases. This study evaluated the clinical significance of measuring serum levels of soluble VCAM-1 in rectal cancer and aimed to clarify the biologic significance of its local expression. Method: Serum was collected from 90 patients with rectal cancer and 40 healthy volunteers. Cancer tissue...

Serum levels of soluble intercellular adhesion molecule-1 (s-ICAM-1) and soluble endothelial leukocyte adhesion molecule-1(s-ELAM-1) in amyotrophic lateral sclerosis.

Immunological disturbances have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). Adhesion molecules are markers of activated endothelial cells up-regulated by action of cytokines. To investigate the activation or inactivation of the vascular cells in ALS, serum soluble intercellular adhesion molecule-1 (s-ICAM-1) and soluble E-selectin (s-ELAM-1) were evaluated (ELISA...

Cytokines and soluble intracellular adhesion molecule 1 in the sera of Saudi eczematous children.

We report five children with atopic eczema. The level of soluble adhesion molecules is known to correlate with disease severity. On the assumption that atopic eczema is a T-lymphocyte-mediated inflammatory disease, in this study, we aimed to determine the presence of soluble intracellular adhesion molecule (sICAM) 1 and the release of inflammatory cytokines. The patient sera were used to measur...

Soluble intercellular adhesion molecule-1, soluble vascular adhesion molecule-1, and the development of symptomatic peripheral arterial disease in men.

BACKGROUND Elevated levels of soluble cellular adhesion molecules have been linked to the development of occlusive coronary events in otherwise healthy individuals. It is not certain, however, whether similar relationships exist for the development of early systemic atherosclerosis. METHODS AND RESULTS In a prospective, nested case-control study conducted among 14 916 middle-aged men, we eval...